Hope S. Rugo, MD, FASCO is Professor of Medicine and Director of Breast Oncology and Clinical Trials Education at the UCSF Helen Diller Family Comprehensive Cancer Center. An internationally recognized breast cancer researcher and clinician, she leads multiple trials on targeted therapies, immunotherapy, and toxicity reduction. She serves in leadership roles for the I-SPY2 trial, the Translational Breast Cancer Research Consortium, and ASCO’s Guidelines Committee, and has published widely on advancing treatment for early and metastatic breast cancer.